RESEARCH & EXPERIENCE
Connecting nutritional metabolism, analytical chemistry, and biomarker discovery to understand individual differences in cardiometabolic health.
My research focuses on precision nutrition and the metabolic pathways through which diet and genetic variation influence cardiovascular disease risk. I integrate metabolomics and lipidomics in clinical human samples and mouse models to characterize metabolic phenotypes and identify candidate biomarkers that may inform more individualized nutritional strategies.
My training spans hands-on LC–MS/MS platform operation, method development and optimization, sample preparation, quality control, and statistical analysis. I’m motivated by research that connects reliable molecular measurements with biological interpretation and advances the evidence base for precision nutrition.
01 / HUMAN METABOLOMICS & LIPIDOMICS
How do metabolic and lipid profiles differ across cardiovascular risk levels in otherwise clinically healthy adults?
I integrate hundreds of metabolites and more than 600 lipid species with clinical risk factors, focusing on sphingolipid and serine/one-carbon metabolism.
02 / APOE × DIET
How do APOE genetic backgrounds change the way diet reshapes lipid metabolism over time?
I co-lead a longitudinal mouse study comparing APOE2, APOE3, and APOE4 under Western and Mediterranean dietary exposures, connecting plasma measurements with tissue lipid profiles.
Nutritional Biology · University of California, Davis
My doctoral research integrates metabolomic and lipidomic profiling of human clinical samples and mouse models to investigate cardiovascular risk. I work across study planning, sample preparation, LC–MS/MS acquisition, quality control, and interpretation of molecular profiles.
I independently optimized a SCIEX triple-quadrupole lipidomics workflow, improving analytical sensitivity by approximately 50%, and established standardized quality-control procedures for reproducible lipid measurements.
I characterize skin-surface lipid remodeling during an 18-week study comprising a six-week habitual-diet period followed by 12 weeks of walnut consumption. Targeted LC–MS/MS measurements support longitudinal assessment of lipid responses to dietary change.
I have developed the scientific rationale and analytical framework for exploratory profiling of cardiac tissue from mice expressing human APOE isoforms. This work examines tissue-specific lipid patterns alongside circulating profiles, with attention to sphingolipid pathways.
University of California, Riverside
I supported structural and biochemical studies of DNMT3B variants and ZCCHC4 through supervised recombinant protein production and purification.
My work included primer design, recombinant DNA construct preparation, cell culture, protein expression, and multistep purification using affinity, ion-exchange, and size-exclusion chromatography, including HPLC-based separation. I also performed Western blot analysis and prepared purified proteins for crystallization studies.
The protein preparations and supporting data contributed to two peer-reviewed publications as a co-author.
Vitance Technology (Shenzhen) Co., Ltd.
I help translate nutrition research into personalized assessment and recommendation frameworks. This includes evaluating supplement evidence, designing questionnaires, and developing recommendation logic with product and UI teams.
Teaching experience spanning nutrition, metabolism, genetics, and chemistry.